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- Rinri Therapeutics raises £10 million to advance stem cell therapy for hearing loss
Rinri Therapeutics raises £10 million to advance stem cell therapy for hearing loss University of Sheffield spinout company, Rinri Therapeutics, has raised investment to advance its therapy for hearing lossThe company is developing a novel stem cell therapy to restore hearing and reverse sensorineural hearing lossThere are currently no pharmacological treatments available for this type of hearing lossUniversity of Sheffield spinout company, Rinri Therapeutics, has raised a total of £10 million from investors and the UK Future Fund to advance its novel stem cell therapy to restore hearing loss.The biotechnology company is developing a novel stem cell therapy to restore hearing and will use the £10 million raised from existing investors, Boehringer Ingelheim Venture Fund (BIVF), UCB Ventures and BioCity alongside the UK Government Future Fund, to support the development of its novel stem cell therapy to reverse sensorineural hearing loss (SNHL).Rinri’s underlying technology is based on innovative research into auditory stem cells led by Professor Marcelo Rivolta at the University of Sheffield. It seeks to reverse SNHL through the repair of the damaged cytoarchitecture in the inner ear.SNHL happens when there is damage to the hair cells in the cochlea and/or to the auditory nerve. There are currently no pharmacological treatments available for SNHL despite the increasing number of patients that suffer from this condition globally.Professor Marcelo Rivolta, said: “This investment is a validation of the journey we started several years ago. We are very happy and grateful for the continued support from our investors, now together with the UK Future Fund. We believe the technology we are developing can have a substantial impact on the lives of people affected by hearing loss, and these funds will help us pave the way to a first in man clinical trial.”Dr Simon Chandler, CEO of Rinri Therapeutics, commented: “We are very pleased to receive continuing support from existing investors alongside matched funding from the UK Future Fund. Our major investors share the vision we have for our technology to bring transformational changes to the lives of patients suffering from hearing loss, and the proceeds from this fund raising will allow us to advance our pioneering journey towards first in-man clinical trials and to ultimately realise the potential of stem cell therapy to reverse sensorineural hearing loss.”Frank Kalkbrenner, Global Head of the Boehringer Ingelheim Venture Fund, said: “We are delighted to continue our backing of Rinri and its pioneering approach to hearing loss, now with the added endorsement and support of the Future Fund. We believe Rinri’s’ technology is differentiated from other approaches to hearing loss restoration and has the potential to make a significant impact on treatment.”Additional information Rinri Therapeutics is a private biotechnology company developing advanced stem cell-based therapeutics to restore hearing. The company’s pioneering technology seeks to reverse sensorineural hearing loss (SNHL) through the repair of the damaged cytoarchitecture in the inner ear. SNHL is estimated to affect 64 million patients in the US and 34 million in Europe. There are currently no pharmacological treatment options for SNHL patients.Rinri, is backed by Boehringer Ingelheim Venture Fund (BIVF), UCB Ventures, BioCity and the University of Sheffield. Rinri was founded in late-2018 and is headquartered in Sheffield, UK. /Public Release. This material comes from the originating organization and may be of a point-in-time nature, edited for clarity, style and length. View in full here. Why?Well, unlike many news organisations, we have no sponsors, no corporate or ideological interests. We don’t put up a paywall – we believe in free access to information of public interest. Media ownership in Australia is one of the most concentrated in the world (Learn more). Since the trend of consolidation is and has historically been upward, fewer and fewer individuals or organizations control increasing shares of the mass media in our country. According to independent assessment, about 98% of the media sector is held by three conglomerates. This tendency is not only totally unacceptable, but also to a degree frightening). Learn more hereWe endeavour to provide the community with real-time access to true unfiltered news firsthand from primary sources. It is a bumpy road with all sorties of difficulties. We can only achieve this goal together. Our website is open to any citizen journalists and organizations who want to contribute, publish high-quality insights or send media releases to improve public access to impartial information. You and we have the right to know, learn, read, hear what and how we deem appropriate.Your support is greatly appreciated. All donations are kept completely private and confidential.Thank you in advance!Tags:biotechnology, cell therapy, clinical trials, Europe, Government, Investment, Professor, Sheffield, stem cells, technology, therapeutics, treatment, UK, UK Government, university, University of Sheffield
- What to do if you’re worried about a friend
Suicide – it’s not an easy topic to talk about, but it is so important. Suicide is the second leading cause of death among college-aged students. Whether you or someone you care about is having a hard time, it’s important for someone who is thinking about suicide to get the help they need.Here are a few things you can do if you or someone you know is thinking about suicide:Ask the questionA lot of us are afraid that asking if someone is thinking about suicide can plant the idea or make them think about it more. Research shows that this is not true. Instead, by asking “Have you had thoughts about suicide?” we communicate that we really care about the person. Asking the question can start the conversation to help support them in getting the help they need.ResourcesWhether you’re calling for yourself or for a friend, there are resources available to support you.If someone is in immediate risk of hurting themselves or someone else, call 911.Counseling and Psychiatric Services (CAPS) on campus offers virtual counseling and crisis care services during normal business hours. Anyone can call their main line at 303-492-2277 to speak with a licensed professional 24/7.The National Suicide Prevention Lifeline offers free and confidential support and can be reached 24/7 at 1-800-273-8255.The Crisis Text Line offers free, 24/7 support for those in crisis. Text HOME to 741741 to text with a trained Crisis Counselor.Colorado Crisis Services also offers walk-in and crisis intervention services at a variety of locations throughout Colorado. They can be reached 24/7 at 1-844-493-8255.Know the signsWe can look out for a number of different signs to know when it’s time to ask the question. For example, if someone has expressed that they feel like a burden, has become isolated, has stopped doing things they love, is no longer caring for themselves, or starts talking about wanting to die, you might ask if they’ve had thoughts about suicide.Have a plan to reach outWhen we feel depressed, anxious, or some combination of both, we can easily become isolated and feel like a burden. Even if you doubt it, someone cares about you and wants you around. Studies show that when people write down who they would reach out to if they were in a crisis or felt suicidal, they are less likely to act on suicidal thoughts; try this strategy out for yourself and encourage friends to as well (by doing so, you also show them that you are someone they can reach out to).Supporting a friendAcknowledge their distress. Let them know you hear them.Be direct. Talk openly about suicide, your concerns and what you have noticed.Listen without judgment. Allow them to express their feelings and concerns without lecturing or giving them advice.Encourage them to seek help. If they feel comfortable with you, ask if you can help them connect with a resource. Never promise to keep their thoughts of suicide a secret.Follow up. Check in with your friend about what they need, where they are, and how you can support them.Remember that you are not responsible for the outcome. Getting someone connected to a professional resource is the best thing that you can do. If you’re unsure about what to do, you can reach out to a professional to help you plan your next steps.Counseling worksResearch demonstrates that talking to a mental health professional can help with reframing our thoughts and reducing suicidal ideation. Students who go to their counseling center are 14% more likely to succeed academically than those who do not. Medication distributed by a licensed professional can also be effective in helping people feel like themselves again. Learn more about counseling options available at CU Boulder.Learn more about CU’s suicide prevention campaign.More Health & Wellness ArticlesCategories:Emotional HealthSocial HealthTags:Mental HealthRelationshipsSuicide